Free Essays on Tamoxifen

TAMOXIFEN 1. Why shouldn’t everyone all women take the drug tamoxifen? Which category of women may be helped? Why might â€Å"more women be harmed than helped? It couldn’t be determined which women were at high risk. It was not sure that tamoxifen would not cure breast cancer â€Å"but prevent it.† Many women have died or developed cancer of the uterine lining or blood clots. 2. How does tamoxifen work in the body? It prevents the hormone estrogen from over stimulating breast tissue. PATTERN AND OBSERVATION: It prevents the hormone estrogen from over stimulating breast tissue. PREDICTION: If 85 women developed cancer when they took tamoxifen against against 154 women who took a placebo. Then: Tamoxifen should be given to the 154 who have developed cancer. EXPERIMENT: Remove breast tissue from both category of women to see what is causing the cancer. PATTERN OF RESULTS: The % of women should be less in developing breast cancer when tamoxifen is used. 4. What causes tamoxifen to develop blood clots or cancer of the uterine lining in women. 5. Retest tamoxifen to find out what caused the lining of the uterus to be cancerous in 33 women tested. b. test the placebo to see what it contains that prevents less women to develop breast cancer than when they used tamoxifen. c. inject good tissue with cancerous cells to see if it develops cancer. d. Does the lining of the uterus contain the same gene as breast tissue. Hence the development of cancer of the uterine lining. HERCEPTI N: Herceptin should only be given to women with advanced breast cancer. b. women with mestastic breast cancer whose tumors produced excessive amounts of HER2 receptors. OBSERVATION: Herceptin targets a special gene alteration linked to the cancer. HYPOTHESIS: HERC... Free Essays on Tamoxifen Free Essays on Tamoxifen TAMOXIFEN 1. Why shouldn’t everyone all women take the drug tamoxifen? Which category of women may be helped? Why might â€Å"more women be harmed than helped? It couldn’t be determined which women were at high risk. It was not sure that tamoxifen would not cure breast cancer â€Å"but prevent it.† Many women have died or developed cancer of the uterine lining or blood clots. 2. How does tamoxifen work in the body? It prevents the hormone estrogen from over stimulating breast tissue. PATTERN AND OBSERVATION: It prevents the hormone estrogen from over stimulating breast tissue. PREDICTION: If 85 women developed cancer when they took tamoxifen against against 154 women who took a placebo. Then: Tamoxifen should be given to the 154 who have developed cancer. EXPERIMENT: Remove breast tissue from both category of women to see what is causing the cancer. PATTERN OF RESULTS: The % of women should be less in developing breast cancer when tamoxifen is used. 4. What causes tamoxifen to develop blood clots or cancer of the uterine lining in women. 5. Retest tamoxifen to find out what caused the lining of the uterus to be cancerous in 33 women tested. b. test the placebo to see what it contains that prevents less women to develop breast cancer than when they used tamoxifen. c. inject good tissue with cancerous cells to see if it develops cancer. d. Does the lining of the uterus contain the same gene as breast tissue. Hence the development of cancer of the uterine lining. HERCEPTI N: Herceptin should only be given to women with advanced breast cancer. b. women with mestastic breast cancer whose tumors produced excessive amounts of HER2 receptors. OBSERVATION: Herceptin targets a special gene alteration linked to the cancer. HYPOTHESIS: HERC...